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Current endovascular therapy for lower extremity peripheral arterial disease: indications, outcomes and modalities
  1. B P Yan1,
  2. T J Kiernan2,
  3. Y-Y Lam1,
  4. C-M Yu1
  1. 1Division of Cardiology, Department of Medicine & Therapeutics, Prince of Wales Hospital and The Chinese University of Hong Kong, Hong Kong
  2. 2Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston Massachusetts, USA
  1. Correspondence to B P Yan, Division of Cardiology, Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; bryan.yan{at}cuhk.edu.hk

Abstract

Atherosclerosis of the lower extremities frequently leads to lifestyle-restricting claudication and can cause critical limb ischaemia (rest pain, non-healing ulcer, or gangrene). The prevalence of peripheral arterial disease (PAD) is rising in line with an ageing population. In the USA, PAD affects 8–10 million people (approximately 12% of the adult population). There is a strong association with concomitant coronary artery and cerebral vascular disease in these patients, which represents a significant cause of mortality and morbidity in patients with PAD. Disease affecting the lower extremity peripheral vessels is most aggressive in smokers and diabetics.

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Footnotes

  • Competing interests None declared.

  • Provenance and Peer review Not commissioned; externally peer reviewed.

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