Article Text

PDF
Anthropometric measurements for the prediction of the metabolic syndrome: a cross-sectional study on adolescents and young adults from southern india
  1. S K Vasan1,4,
  2. N Thomas1,
  3. S Christopher2,
  4. F S Geethanjali3,
  5. T V Paul1,
  6. C B Sanjeevi4
  1. 1Department of Endocrinology, Diabetes & Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India
  2. 2Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India
  3. 3Department of Clinical Biochemistry, Christian Medical College & Hospital, Vellore, Tamil Nadu, India
  4. 4Department of Molecular Medicine & Surgery, Karolinska INSTITUTET, Stockholm, Sweden
  1. Correspondence to Professor Nihal Thomas, Department of Endocrinology, Diabetes & Metabolism, Christian Medical College & Hospital, Vellore 632004, Tamil Nadu, India; nihal_thomas{at}yahoo.com

Abstract

Objectives To determine which anthropometric measurement correlates best with the metabolic abnormalities associated with the metabolic syndrome in adolescents and young adults.

Design Cross-sectional study.

Setting Schools, high schools and universities.

Participants 1359 adolescents and young adults aged 14–25 years.

Main outcome measures Anthropometric predictors of metabolic abnormalities as classified by International Diabetes Federation definition.

Results The waist circumference (OR 1.56, 95% CI 1.0 to 2.43: p≤0.01) and the abdominal skin fold thickness (OR 1.44, 95% CI 1.02 to 2.04, p≤0.01) above the third quintile cut-offs were found to be significantly associated with metabolic abnormalities. The sensitivity of either one of these measurements in predicting metabolic abnormalities was 66.1% with a negative predictive value of 82.8%. Hyperglycaemia was significantly associated with an abdominal skin fold thickness over the fourth quintile alone (OR 1.63, 95% CI 1.24 to 2.1). All the anthropometric measurements correlated well with elevated triglycerides and hypertension.

Conclusions In a large community-based cross-sectional survey of subjects aged 14–25 years, the waist circumference and the abdominal skin fold thickness are important predictors of the metabolic abnormalities associated with metabolic syndrome. This simple clinical tool may help in a primary care setting to identify subjects who require a further biochemical evaluation and would considerably reduce the cost of unwarranted testing.

  • Metabolic syndrome
  • adolescents
  • anthropometry
  • skin fold thickness
  • waist circumference

Statistics from Altmetric.com

Footnotes

  • Funding This study was partially funded by grants from Research Society for Study of Diabetes in India and Pfizer Pharmaceuticals R & D.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval Ethics approval was provided by the Institituional Review Board and Ethics Committee of Christian Medical College, Vellore, Tamil Nadu, India.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.