Clinical and laboratory parameters of subjects with and without cardiac disease
| Parameters | Cardiac disease, n=85 | No cardiac disease, n=115 | χ2 | p Value |
|---|---|---|---|---|
| Duration of HIV ≥40 months | 49 (34) | 41 (36) | 1.57 | 0.04 |
| HAART use, n (%) | 67 (78.8) | 101 (87.8) | 2.95 | 0.09 |
| Duration on HAART in months, mean (SD) | 39 (23) | 42 (24.0) | 0.91 | 0.36 |
| History of past TB treatment, n (%) | 21 (25) | 32 (28.0) | 0.20 | 0.66 |
| WHO staging of HIV/AIDS, n (%): | 4.26 | 0.04 | ||
| 1 | 26 (31.0) | 46 (38.6) | ||
| 2 | 20 (28.8) | 35 (30.7) | ||
| 3 | 30 (35.7) | 31 (27.2) | ||
| 4 | 8 (9.5) | 4 (3.5) | ||
| NYHA dyspnoea class, n (%): | 5.07 | 0.02 | ||
| I | 13 (15.3) | 17 (15.0) | ||
| II | 5 (5.9) | 11 (9.2) | ||
| III | 21 (24.7) | 16 (14.2) | ||
| IV | 7 (8.2 | 0 (0.0) | ||
| BMI, mean (SD) | 23.9 (5.0) | 24.4 (4.5) | 0.83 | 0.41 |
| SBP, mean (SD) | 118 (15.9) | 119 (19.0) | 0.57 | 0.57 |
| DBP, mean (SD) | 77 (11.7) | 78 (11.0) | 0.07 | 0.94 |
| Hb concentration, mean (SD) | 11.9 (2.0) | 12.3 (1.8) | 1.57 | 0.12 |
| CD4 cell count, median | 193 | 459 | 6.83 | <0.001 |
| Log 10 viral load, mean (SD) | 3.16 (1.1) | 3.22 (1.1) | 0.3 | 0.7 |
Heart disease=presence of HIV-related cardiac disease (HRCD) or HRPH.
BMI, body mass index; DBP, diastolic blood pressure; HAART, highly active anti-retroviral therapy; Hb, haemoglobin concentration; NYHA, New York Heart Association; SBP, systolic blood pressure; TB, tuberculosis.