Patient demographics
| Demographics | HPR group (n=84) | NPR group (n=310) | p Value |
|---|---|---|---|
| Age (years) | 67.6±9.9 | 65.7±10.5 | NS |
| Gender (female %) | 41.7 | 27.1 | 0.01 |
| Risk factors/medical history | |||
| Smoking (%) | 8.3 | 11.9 | NS |
| Hypertension (%) | 71.4 | 69.0 | NS |
| Diabetes (%) | 39.3 | 30.0 | NS |
| Hyperlipidaemia (%) | 13.1 | 10.6 | NS |
| Prior MI (%) | 23.1 | 14.3 | NS |
| ACS (%) | 53.6 | 58.1 | NS |
| LVEF (%) | 51.2±7.2 | 51.7±10.1 | NS |
| Laboratory data | |||
| Platelets (×109/l) | 187.5±53.4 | 185.1±56.2 | NS |
| FBG (mmol/l) | 7.5±3.0 | 6.8±2.7 | NS |
| HbA1c (>6.5%) (%) | 45.2 | 30.0 | 0.009 |
| CRP (mmol/l) | 4.3±1.9 | 3.6±1.2 | NS |
| TC (mmol/l) | 4.8±1.5 | 4.3±1.1 | 0.002 |
| TG (mmol/l) | 2.2±1.8 | 2.0±1.6 | NS |
| LDL-C (mmol/l) | 2.8±1.1 | 2.5±0.9 | 0.022 |
| HDL-C (mmol/l) | 1.0±0.2 | 0.9±0.3 | NS |
| CK-MB (ng/ml) | 3.4±1.8 | 2.1±1.6 | NS |
| TnI (ng/ml) | 0.7±0.3 | 0.6±0.4 | NS |
ACS, acute coronary syndrome; CK-MB, creatine kinase MB; CRP, C-reactive protein; FBG, fasting blood glucose; HbA1c, glycosylated haemoglobin; HDL-C, high-density lipoprotein cholesterol; HPR, high on-treatment platelet reactivity; LDL-C, low-density lipoprotein cholesterol; LVEF, left ventricular ejection fraction; MI, myocardial infarction; NPR, normal on-treatment platelet reactivity; TC, total cholesterol; TG, triglycerides; TnI, troponin I.