Table 1 ACC/AHA guidelines for endovascular therapy in peripheral arterial disease4
IndicationRecommendationLevel of evidence
Claudication:
Class IEVT is indicated for vocational or lifestyle-limiting disability due to IC if there is reasonable likelihood of symptomatic improvement with EVT and (a) response to exercise or pharmacological therapy is inadequate and/or (b) favourable risk/benefit ratio (eg, focal aortoiliac occlusive disease)A
EVT is preferred revascularisation technique for simple iliac and femoropopliteal arterial lesionsB
Provisional stent placement in iliac arteries for suboptimal or failed result from balloon dilationB
Stenting is effective as primary therapy for common iliac and external iliac artery stenoses and occlusionsB and C
Class IIaStents (and other adjunctive techniques such as lasers, cutting balloons, atherectomy devices and thermal devices) can be useful in the femoral, popliteal and tibial arteries for a suboptimal or failed result from balloon dilationC
Class IIIPrimary stent placement is not recommended in the femoral, popliteal, or tibial arteriesC
EVT is not indicated as prophylactic therapy in a patient who is asymptomatic with lower extremity PADC
Critical limb ischaemia:
Class IInflow lesions should be revascularised firstC
Outflow revascularisation should be performed when symptoms of CLI or infection persist after inflow revascularisation.B
Class IIIEVT is not indicated in patients with severe decrements in limb perfusion (eg, ABI<0.4) in the absence of clinical symptoms of CLIC
  • ABI, ankle–brachial index; ACC, American College of Cardiology; AHA, American Heart Association; CLI, critical limb ischaemia; EVT, endovascular therapy; IC, intermittent claudication; PAD, peripheral arterial disease.