Study centres and patients in China
| No. of patients | |||||
|---|---|---|---|---|---|
| Investigator and affiliation | Total enrolled | Total randomised | Riociguat 2.5 mg-maximum dose | Riociguat 1.5 mg-maximum dose | Placebo |
| PATENT-1 | 83 | 77 | 43 | 10 | 24 |
| Professor Jian-Guo He (Lead investigator) Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China | 13 | 13 | 8 | 0 | 5 |
| Professor Zhi-Cheng Jing Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China | 23 | 21 | 12 | 5 | 4 |
| Professor Da-Xin Zhou Donghua Zhou, School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China | 12 | 12 | 5 | 2 | 5 |
| Professor Yi-Gao Huang Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong Guangdong General Hospital and Guangdong Cardiovascular Institute, Guangzhou, Guangdong, China | 16 | 13 | 8 | 2 | 3 |
| Professor Chen Wang Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China Department of Beijing Hospital, Ministry of Health, Beijing, China | 19 | 18 | 10 | 1 | 7 |
| CHEST-1 | 58 | 32 | 21 | – | 11 |
| Associate Professor Zhi-Hong Liu Centre for Pulmonary Vascular Diseases, Fuwai Hospital and Cardiovascular Institute, Beijing, China | 7 | 4 | 3 | – | 1 |
| Professor Chen Wang Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, PR China Department of Beijing Hospital, Ministry of Health, Beijing, China | 32 | 21 | 15 | – | 6 |
| Professor Zhao-Zhong Cheng The Affiliated Hospital of Medical College of Qingdao, Shandong, China | 3 | 0 | 0 | – | 0 |
| Professor Zhi-Cheng Jing Tongji University Affiliated Shanghai Pulmonary Hospital, Shanghai, China Thrombosis and Vascular Medicine Centre, State Key Lab of Cardiovascular Disease, Fuwai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China | 14 | 7 | 3 | – | 4 |
| Professor Lei Pan Capital Medical University, Beijing, China | 2 | 0 | 0 | – | 0 |
| Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China | |||||