Table 2

Comparison of 99th percentile values in men, women and mixed gender populations (general, non-cardiac or healthy individuals) in different studies using the Abbott ARCHITECT STAT high-sensitivity troponin I package

					99th percentile (ng/L)
Source	Country	Age (years)	Specimen type	n	Female	Male	Overall
Package insert	USA	18–75	All	4593	15.6	34.2	26.2
			EDTA	1531	16.7	35.1	27.8
			Serum	1529	14.7	32.1	22.3
			Lithium heparin	1531	14.3	34.5	26.9
Apple et al 20128	USA	18–64	Lithium heparin	524	15	36	23
Koerbin et al 201218	Australia	20–84	Serum	497	11.1	14.0	13.6
Aw et al 20139	Singapore	35–65	Serum	1120	17.9	32.7	25.6
Krintus et al 201415	Europe*	18–91	Serum	1769	11.4	27	19.3
Zeller et al 201419	Scotland	40–59	Serum	12 650	18.1	31.7	23.9
Collinson et al 201517	England	45–89	Serum	599	9.9	28.5	21.0
Zeller et al 201516	Germany	35–75	Serum	4138	19.9	33.1	27.0

*Nine laboratories in Austria, Belgium, Denmark, France, Germany, Italy, Norway, Poland and Spain.