Table 3

ORs for maternal pregnancy complications†

Pregnancy complicationsOR (95% CI)p Value
Overall pregnancy complications
 Crude‡2.90 (1.41 to 5.95)0.004*
 Model 1§3.16 (1.42 to 7.08)0.005*
 Model 2¶4.06 (1.68 to 9.79)0.002*
 Model 3**3.25 (1.27 to 8.28)0.014*
 Model 4††4.47 (1.10 to 18.13)0.036*
Maternal high blood pressure
 Crude‡3.00 (0.81 to 11.08)0.099
 Model 1§5.18 (1.02 to 26.33)0.048*
 Model 2¶4.80 (1.03 to 22.48)0.046*
 Model 3**4.83 (0.81 to 28.68)‡‡0.083‡‡
 Model 4§§4.96 (1.00 to 24.66)0.050*
Maternal infections
 Crude‡3.17 (1.27 to 7.93)0.014*
 Model 1§3.00 (1.14 to 7.90)0.026*
 Model 2¶3.66 (1.30 to 10.26)0.014*
 Model 3**2.81 (0.94 to 8.37)‡‡0.064‡‡
 Model 4††5.21 (1.13 to 24.20)0.035*
  • *p<0.05.

  • †Univariable and multivariable analyses were done by conditional logistic regression for matched data.

  • ‡Crude was univariable analysis.

  • §Model 1 was adjusted for current smoking status, high salty food and MSG intake, high fatty food intake, monthly income and college education.

  • ¶Model 2 was Model 1 plus adjusted for parental history of CVD.

  • **Model 3 was Model 2 plus adjusted for childhood infections.

  • ††Model 4 was Model 3 plus adjusted for adulthood cardiovascular risk factors (hypertension, raised fasting plasma glucose, LDL-cholesterol, HDL-cholesterol and BMI).

  • ‡‡Multicollinearity was assumed.

  • §§Model 4 was not adjusted for offspring adulthood hypertension and childhood infections because of strong collinearity among these variables.

  • BMI, body mass index; CVD, cardiovascular disease; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MSG, monosodium glutamate.