Catheter technique for closed-chest ablation of the atrioventricular conduction system: a therapeutic alternative for the treatment of refractory supraventricular …

JJ Gallagher, RH Svenson, JH Kasell… - … England Journal of …, 1982 - Mass Medical Soc
This report describes a catheter technique for ablating the His bundle and its application in
nine patients with recurrent supraventricular tachycardia that was unresponsive to medical …

[HTML][HTML] Adverse consequences of high sympathetic nervous activity in the failing human heart

DM Kaye, J Lefkovits, GL Jennings, P Bergin… - Journal of the American …, 1995 - Elsevier
OBJECTIVES.: In view of previous experimental evidence relating sympathetic nervous
overactivity in the heart to myocardial necrosis and ventricular arrhythmias, we prospectively …

[HTML][HTML] Evidence of a selective increase in cardiac sympathetic activity in patients with sustained ventricular arrhythmias

IT Meredith, A Broughton, GL Jennings… - New England Journal …, 1991 - Mass Medical Soc
Background. Although enhanced efferent cardiac sympathetic nervous activity has been
proposed as an important factor in the genesis of ventricular arrhythmias and sudden …

Combined dyssynchrony and scar imaging with cardiac magnetic resonance imaging predicts clinical response and long-term prognosis following cardiac …

AJ Taylor, M Elsik, A Broughton, J Cherayath, A Leet… - Europace, 2010 - academic.oup.com
Aims Cardiac resynchronization therapy (CRT) is advocated in advanced heart failure;
however, patient selection remains challenging. We examined the utility of multi-sequential …

Steady-state effects of preload and afterload on isovolumic indices of contractility in autonomically blocked dogs

A BROUGHTON, PI KORNER - Cardiovascular Research, 1980 - academic.oup.com
The steady-state effects of independently altering left atrial pressure (LAP), aortic pressure
(AP), and heart rate (HR) on left ventricular isovolumic indices were studied in autonomically …

Effects of exercise and isoproterenol during atrial fibrillation in patients with Wolff-Parkinson-White syndrome

LD German, JJ Gallagher, A Broughton… - The American journal of …, 1983 - Elsevier
The effects of exercise and isoproterenol on atrial fibrillation (AF) were studied in 17 patients
with Wolff-Parkinson-White syndrome (WPW) to assess the risk of developing a rapid …

Bystander accessory pathway during AV node re‐entrant tachycardia

WM Smith, A Broughton, MJ Reiter… - Pacing and Clinical …, 1983 - Wiley Online Library
Between 1970 and July 1980, wide QRS tachycardia due to re‐entryconfined to the AV node
with bystander involvement of an accessory atrioventricular pathway (AAV) was documented …

Lipid solubility modulates pH potentiation of local anesthetic block of Vmax reactivation in guinea pig myocardium.

A Broughton, AO Grant, CF Starmer, JK Klinger… - Circulation …, 1984 - Am Heart Assoc
Current theories envision recovery from local anesthetic block of sodium channels via slow
hydrophilic and fast hydrophobic paths. Extracellular pH reduction which increases …

Left ventricular pump function in renal hypertensive dogs with cardiac hypertrophy

A Broughton, PI Korner - American Journal of Physiology …, 1986 - journals.physiology.org
We compared open-chest left ventricular (LV) pump performance after autonomic blockade
under controlled loading conditions in normal dogs and in dogs where chronic renovascular …

Comparison of left and right ventricular blood flow responses during arterial pressure reduction in the autonomically blocked dog: evidence for right ventricular …

JJ SMOLICH, PL WEISSBERG… - Cardiovascular …, 1988 - academic.oup.com
The effect of reducing systemic arterial pressure with an arteriovenous fistula on left and
right ventricular myocardial blood flow was studied in 17 anaesthetised, open chest …