User profiles for "author:Archana Shrestha"

Archana Shrestha

Kathmandu University School of Medical Sciences
Verified email at kusms.edu.np
Cited by 1184

Towards an understanding of the role of Clostridium perfringens toxins in human and animal disease

FA Uzal, JC Freedman, A Shrestha, JR Theoret… - Future …, 2014 - Future Medicine
Clostridium perfringens uses its arsenal of> 16 toxins to cause histotoxic and intestinal
infections in humans and animals. It has been unclear why this bacterium produces so many …

[HTML][HTML] Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications

JC Freedman, A Shrestha, BA McClane - Toxins, 2016 - mdpi.com
Clostridium perfringens enterotoxin (CPE) is responsible for causing the gastrointestinal
symptoms of several C. perfringens food-and nonfood-borne human gastrointestinal …

Pathogenicity and virulence of Clostridium perfringens

I Mehdizadeh Gohari, M A. Navarro, J Li, A Shrestha… - Virulence, 2021 - Taylor & Francis
Clostridium perfringens is an extremely versatile pathogen of humans and livestock, causing
wound infections like gas gangrene (clostridial myonecrosis), enteritis/enterocolitis …

Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands

MÁ Tormo-Más, I Mir, A Shrestha, SM Tallent… - Nature, 2010 - nature.com
Staphylococcal superantigen-carrying pathogenicity islands (SaPIs) are discrete,
chromosomally integrated units of∼ 15 kilobases that are induced by helper phages to …

[HTML][HTML] Prevalence and associated factors of childhood overweight/obesity among primary school children in urban Nepal

A Karki, A Shrestha, N Subedi - BMC public health, 2019 - Springer
Background Childhood overweight/obesity has become a major public health concern
globally because of its adverse health consequences and escalating prevalence. The …

Comparative pathogenesis of enteric clostridial infections in humans and animals

FA Uzal, MA Navarro, J Li, JC Freedman, A Shrestha… - Anaerobe, 2018 - Elsevier
Several enteric clostridial diseases can affect humans and animals. Of these, the enteric
infections caused by Clostridium perfringens and Clostridium difficile are amongst the most …

[HTML][HTML] Patient satisfaction and its socio-demographic correlates in a tertiary public hospital in Nepal: a cross-sectional study

M Adhikari, NR Paudel, SR Mishra, A Shrestha… - BMC health services …, 2021 - Springer
Background Patient satisfaction is one proxy indicator of the health care quality; however,
enhancing patient satisfaction in low-income settings is very challenging due to the …

Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology

N Bakeer, J James, S Roy… - Proceedings of the …, 2016 - National Acad Sciences
Cardiopulmonary complications are the leading cause of mortality in sickle cell anemia
(SCA). Elevated tricuspid regurgitant jet velocity, pulmonary hypertension, diastolic, and …

Awareness, treatment and control of hypertension in Nepal: findings from the Dhulikhel Heart Study

BM Karmacharya, RP Koju, JP LoGerfo, KCG Chan… - Heart …, 2017 - heartasia.bmj.com
Objectives Although previous studies have suggested alarming rise in the prevalence of
hypertension in Nepal, there is dearth of information on its awareness, treatment and control …

[HTML][HTML] Frontline healthcare workers' knowledge and perception of COVID-19, and willingness to work during the pandemic in Nepal

DP Upadhyaya, R Paudel, D Acharya, K Khoshnood… - Healthcare, 2020 - mdpi.com
This study investigated the contextual factors associated with the knowledge, perceptions,
and the willingness of frontline healthcare workers (FHWs) to work during the COVID-19 …