Responses

PDF
DKA-induced Brugada phenocopy mimicking STEMI
Compose Response

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Statement of Competing Interests

PLEASE NOTE:

  • Responses are moderated before posting and publication is at the absolute discretion of BMJ, however they are not peer-reviewed
  • Once published, you will not have the right to remove or edit your response. Removal or editing of responses is at BMJ's absolute discretion
  • If patients could recognise themselves, or anyone else could recognise a patient from your description, please obtain the patient's written consent to publication and send them to the editorial office before submitting your response [Patient consent forms]
  • By submitting this response you are agreeing to our full [Response terms and requirements]

Vertical Tabs

Other responses

Jump to comment:

  • Published on:
    Brugada Phenocopy or unmasked Brugada Syndrome: Does observation without therapy is sufficient?
    • Sunil Roy T. Narayanan, Consultant Interventional Cardiologist Belhoul Speciality Hospital, Dubai, UAE
    • Other Contributors:
      • Warkaa Al Shamkhani, Cardiology Registrar

    Dear Editor,
    Cardiac death in patients with Brugada ECG changes and negative family history is still a debatable subject. Brugada Phenocopy (BrP) is an emerging phenomenon describing conditions inducing a Brugada-like electrocardiogram (ECG) manifestations in patients without true BS. Brugada Phenocopy is defined as ECG patterns suggestive of Brugada syndrome but developed secondary to various acquired etiologies other than congenital or genetic causes. BrP cases were reported secondary to electrolyte disturbances, myocardial infarction, acidosis, pulmonary embolism, electrocution injury etc. The pattern presents in relationship with an identifiable condition and normalizes upon resolution of the same. The number of BrP cases are steadily increasing and the number of conditions known to cause Brugada Phenocopy are also growing. The diagnostic criteria for Brugada Phenocopy are (1)
    I. An ECG Pattern that has a type -1 or type-2 Brugada morphology
    II. The patient has an indentifiable underlying condition.
    III. The ECG pattern resolves upon resolution of the underlying condition
    IV. The clinical pretest probability of true Brugada syndrome is low as determined by a lack of symptoms, medical history, and family history
    V. The results of provocative testing with a sodium channel blocker such as ajmaline, flecainide, or procainamide are negative
    VI. Provocative testing is not mandatory if surgical RVOT manipulation has...

    Show More
    Conflict of Interest:
    None declared.