RT Journal Article
SR Electronic
T1 Predictors of cardiac benefits of renal artery stenting from a multicentre retrospective registry
JF Heart Asia
FD BMJ Publishing Group Ltd, British Cardiovascular Society and Asia Pacific Heart Association
SP e010934
DO 10.1136/heartasia-2017-010934
VO 9
IS 2
A1 Yuri Nakajima
A1 Osami Kawarada
A1 Akihiro Higashimori
A1 Yoshiaki Yokoi
A1 Kan Zen
A1 Hitoshi Anzai
A1 Hideki Doi
A1 Seiji Hokimoto
A1 Shigenori Ito
A1 Taku Kato
A1 Teruyoshi Kume
A1 Yoshiaki Shintani
A1 Shuzou Tanimoto
A1 Yoshinori Tsubakimoto
A1 Makoto Utsunomiya
A1 Kunihiro Nishimura
A1 Satoshi Yasuda
YR 2017
UL http://heartasia.bmj.com/content/9/2/e010934.abstract
AB Objectives There have been limited data regarding the prediction of cardiac benefits after renal artery stenting for patients with atherosclerotic renal artery disease (ARAD). The aim of this multicentre retrospective study was to identify clinical or echocardiographic factors associated with improvements of cardiac symptoms after renal artery stenting.Methods We enrolled 58 patients with de novo ARAD undergoing successful renal artery stenting for heart failure, angina or both between January 2000 and August 2015 at 13 hospitals.Results Improvement of cardiac symptoms was observed in 86.2% of patients during a mean follow-up of 6.0±2.7 months. Responders demonstrated significantly lower New York Heart Association functional class, higher estimated glomerular filtration rate, lower serum creatinine and lower interventricular septal wall thickness (IVS), lower left ventricular mass index, lower left atrial dimension and lower E-velocity than non-responders. Backward stepwise multivariate analysis identified IVS as an independent predictor of improvement of cardiac symptoms (OR 0.451, 95% CI 0.209 to 0.976; p=0.043). According to receiver operating characteristic curve analysis, an IVS cut-off of 11.9 mm provided the best predictive value, with sensitivity of 71.4%, specificity of 75.5% and accuracy of 73.5%. The positive predictive value was 74.5% and the negative predictive value was 72.5%.Conclusions This multicentre retrospective study shows that the echocardiographic index of IVS is an independent predictor for improvement of cardiac symptoms after renal artery stenting.