RT Journal Article SR Electronic T1 Transmitral inflow wave and progression from paroxysmal to permanent atrial fibrillation in Asian people JF Heart Asia JO Heart Asia FD BMJ Publishing Group Ltd, British Cardiovascular Society and Asia Pacific Heart Association SP e011166 DO 10.1136/heartasia-2018-011166 VO 11 IS 2 A1 Takashi Nakagawa A1 Hisao Hara A1 Masaya Yamamoto A1 Yumi Matsushita A1 Yukio Hiroi YR 2019 UL http://heartasia.bmj.com/content/11/2/e011166.abstract AB Objective Paroxysmal atrial fibrillation could progress to permanent atrial fibrillation. Whether the transmitral inflow waves could be used to predict progression from paroxysmal atrial fibrillation to permanent atrial fibrillation is unknown. Therefore, we investigated the association between the transmitral inflow waves and progression of paroxysmal atrial fibrillation.Method We performed a retrospective study by analysing clinical and echocardiographic data from 88 patients with paroxysmal atrial fibrillation. We excluded patients who had structural heart disease, significant valvular disease, cardiomyopathy, cardiac device implantation or a left ventricular ejection fraction <50%.Result The patients with progression to permanent atrial fibrillation were more likely to be male and had lower peak A velocity than those without progression. After adjusting for covariates, lower peak A velocity remained the independent predictor of progression to permanent atrial fibrillation (p=0.025).Conclusion The A velocity could be useful for predicting progression to permanent atrial fibrillation in Asian people.