Clinical data at baseline and at the follow-up
| Parameters | Baseline (n=28) | Follow-up (n=28) |
| Age (years) | 41.4±9.2 | 43.1±9.7 |
| Sex (male/female) | 12/16 | 12/16 |
| Body surface area (m2) | 1.84±0.3 | 1.85±0.3 |
| Mitoxantrone cumulative dosage (mg/m2) | 30.3±14.5 | 40.9±17.5 |
| Heart rate (beats/min) | 69.9±7.4 | 71.7±8.0 |
| Systolic blood pressure (mm Hg) | 120.0±15.5 | 119.3±15.2 |
| Diastolic blood pressure (mm Hg) | 76.3±10.8 | 79.3±6.8 |
Data are expressed as mean±SD.