mRNA levels of IL6, vWF and P-selectin in ACS and control subjects
Marker | ACS | Controls | p Value |
---|---|---|---|
IL6, median (IQR)* | 0.13 (0.24) | 0.16 (0.31) | 0.536 |
vWF, median (IQR)† | 0.040 (0.01) | 0.0025 (0.01) | 0.227 |
P-selectin, median (IQR)‡ | 388.30 (479.24) | 373.34 (403.65) | 0.675 |
Due to consideration of sample qualities, a varying total number of samples to be analysed for relative mRNA fold change in IL6, vWF and P-selectin were taken. Some samples were also excluded for further analysis as only one replicate recorded a positive CT, and the other was negative (undetected), or showed primer dimer.
*IL6: 12 ACS versus 7 controls.
†vWF: 17 ACS versus 12 controls.
‡P-selectin: 19 ACS versus 12 controls.
ACS, acute coronary syndrome; vWF, von Willebrand Factor.