Table 1 DES on-label and off-label use
On-label use of drug-eluting stents (as approved by regulatory authorities in the USA)
 1. Single de novo lesion in a native coronary artery in patients with stable coronary disease
 2. Lesions covered by one stent with following characteristics:
  Cypher 2.5–3.5 mm RVD*, ⩽30 mm long
  Taxus 2.5–3.75 mm RVD*, ⩽35 mm
Off-label use of drug-eluting stents (use not evaluated in adequately powered randomised studies)
 1. Very small vessels and very long lesions
 2. Acute myocardial infarction
 3. In-stent restenosis
 4. Saphenous venous graft disease
 5. Bifurcation lesions
 6. Left main disease
 7. Chronic total occlusions
 8. Multivessel disease
  • RVD, reference vessel diameter.