Baseline characteristics among 12 759 women and 33 093 men
| Characteristic | Unadjusted | Age-adjusted* | |||
| Women (%) | Men (%) | Women (%) | Men (%) | p Value | |
| Age at entry (years) | |||||
| <55 | 12.7 | 36.6 | |||
| 55–64 | 25.1 | 27.1 | |||
| 65–74 | 43.5 | 27.9 | |||
| ≥75 | 18.7 | 8.3 | |||
| Mean (SD) | 66.6 (9.7) | 59.3 (11.9) | |||
| Time since onset (h) | |||||
| <6 | 29.5 | 35.3 | 30.3 | 34.9 | <0.0001 |
| 6 to <13 | 34.5 | 32.2 | 34.3 | 32.3 | |
| 13–24 | 36.0 | 32.4 | 35.2 | 32.7 | |
| Mean (SD) | 10.8 (6.6) | 10.1 (6.7) | 10.7 | 10.2 | |
| Systolic blood pressure (mm Hg) | |||||
| <120 | 28.7 | 35.5 | 29.5 | 35.1 | <0.0001 |
| 120–139 | 34.9 | 35.5 | 35.2 | 35.4 | |
| 140–159 | 22.0 | 18.8 | 21.4 | 18.9 | |
| ≥160 | 14.3 | 10.3 | 13.4 | 10.4 | |
| Mean (SD) | 131.1 (23.4) | 127.1 (22.1) | 130.5 | 127.3 | |
| Heart rate (bpm) | |||||
| <70 | 19.1 | 23.3 | 18.9 | 23.2 | <0.0001 |
| 70–89 | 47.4 | 49.0 | 47.9 | 48.8 | |
| 90–109 | 24.5 | 21.4 | 24.5 | 21.4 | |
| ≥110 | 9.0 | 6.3 | 8.5 | 6.4 | |
| Mean (SD) | 84.2 (18.0) | 81.4 (16.8) | 84.0 | 81.4 | |
| ECG abnormality at entry | |||||
| Bundle branch block | 5.8 | 6.6 | 4.9 | 6.7 | <0.0001 |
| ST elevation: anterior alone | 47.0 | 50.9 | 47.9 | 50.5 | |
| All other ST elevation | 36.3 | 37.1 | 36.6 | 37.0 | |
| ST depression, without ST elevation | 10.9 | 5.4 | 10.4 | 5.4 | |
| Killip class | |||||
| II or III | 30.5 | 22.2 | 25.7 | 22.6 | <0.0001 |
| Previous disease | |||||
| Previous myocardial infarction | 6.6 | 9.0 | 5.7 | 9.0 | <0.0001 |
| Previous hypertension | 50.6 | 40.4 | 48.1 | 41.0 | <0.0001 |
| Hospital category | |||||
| III (teaching and provincial) | 29.2 | 30.0 | 28.7 | 30.1 | |
| II (medium-sized) | 53.0 | 52.3 | 53.3 | 52.2 | |
| I (small county and district) | 17.8 | 17.8 | 18.0 | 17.7 | 0.02 |
| Drug use | |||||
| Long-term aspirin | 18.2 | 18.5 | 16.7 | 18.7 | <0.0001 |
| Long-term beta-blocker | 6.5 | 6.5 | 6.2 | 6.6 | 0.18 |
| Fibrinolytic agent before randomisation | 41.1 | 53.0 | 44.1 | 51.6 | <0.0001 |
| Fibrinolytic agent in those admitted <13 h after onset† | 49.2 | 60.7 | 52.4 | 59.5 | <0.0001 |
* Age-adjustment is to the average age (61.3 years) of the whole study population.
† 22 360 men and 8164 women.