The effect of iPOST in uraemic and non-uraemic animals on arrhythmia frequency and duration
| Sham SNx | Sham SNx iPOST | SNx | SNx iPOST | p Value | |
|---|---|---|---|---|---|
| Duration of ischaemic arrhythmias | 88 (42–232) | 163 (37–314) | 70 (3–124) | 73 (50–175) | 0.36 |
| Duration of reperfusion arrhythmias | 16 (7–21) | 21 (13–63) | 11 (8–19) | 15 (2–20) | 0.05 |
| Total duration of all arrhythmias | 104 (46–244) | 202 (6–345) | 78 (30–146) | 85 (58–181) | 0.23 |
| Number of arrhythmias occurring during ischaemia | 3 (1–4) | 2 (1–4) | 3 (0–3) | 1 (1–3) | 0.27 |
| Number of arrhythmias occurring during reperfusion | 1 (0–1) | 1 (1–2) | 1 (0–1) | 1 (0–1) | 0.16 |
| Total Number of all arrhythmias | 3 (2–5) | 4 (2–5) | 3 (1–5) | 2 (1–4) | 0.79 |
Four groups were studied; a non-uraemic group (Sham SNx, n=9), an uraemic group (SNx, n=9), a non-uraemic group which underwent an iPOST protocol (Sham SNx iPOST, n=8) and an uraemic group, which underwent an iPOST protocol (SNx iPOST, n=9). Data displayed as median (IQR), with p value calculated using a two-tailed Mann-Whitney U test.
iPOST, ischaemic postconditioning; SNx, subtotal nephrectomy.