Adjusted association between tertile of MPV and clinical outcomes
| Unadjusted | Adjusted* | ||||||
|---|---|---|---|---|---|---|---|
| Events, n (%) | OR | 95% CI | p Value | OR | 95% CI | p Value | |
| Primary outcome | 0.001† | <0.001 | |||||
| Tertile 1 | 92 (24.6) | 1 | 1 | ||||
| Tertile 2 | 84 (25.9) | 1.28 | 0.86 to 1.90 | 1.31 | 0.89 to 1.95 | ||
| Tertile 3 | 116 (35.8) | 2.26 | 1.57 to 3.24 | 2.31 | 1.60 to 3.35 | ||
| Cardiovascular mortality at 1 year | <0.001† | <0.001 | |||||
| Tertile 1 | 20 (5.3) | 1 | 1 | ||||
| Tertile 2 | 16 (4.9) | 0.92 | 0.47 to 1.81 | 0.92 | 0.46 to 1.86 | ||
| Tertile 3 | 42 (13.0) | 2.64 | 1.51 to 4.59 | 2.62 | 1.47 to 4.70 | ||
| Inhospital mortality | 0.096† | 0.196 | |||||
| Tertile 1 | 8 (1.8) | 1 | 1 | ||||
| Tertile 2 | 10 (2.5) | 1.35 | 0.53 to 3.44 | 1.51 | 0.57 to 3.98 | ||
| Tertile 3 | 16 (4.4) | 2.43 | 1.03 to 5.76 | 2.26 | 0.92 to 5.52 | ||
| Fatal or non-fatal myocardial infarction | 0.01† | 0.01 | |||||
| Tertile 1 | 41 (11.0) | 1 | 1 | ||||
| Tertile 2 | 51 (15.7) | 1.38 | 0.89 to 2.13 | 1.29 | 0.83 to 2.00 | ||
| Tertile 3 | 61 (18.8) | 1.92 | 1.26 to 2.93 | 1.92 | 2.25 to 2.95 | ||
| New symptomatic heart failure | 0.542† | 0.41 | |||||
| Tertile 1 | 45 (12) | 1 | 1 | ||||
| Tertile 2 | 39 (12) | 0.92 | 0.59 to 1.44 | 0.85 | 0.54 to 1.36 | ||
| Tertile 3 | 44 (13.6) | 1.18 | 0.76 to 1.84 | 1.18 | 0.74 to 1.86 | ||
| Stroke | 0.12† | 0.183 | |||||
| Tertile 1 | 10 (2.7) | 1 | 1 | ||||
| Tertile 2 | 6 (1.9) | 0.64 | 0.23 to 1.78 | 0.66 | 0.24 to 1.87 | ||
| Tertile 3 | 14 (4.3) | 1.69 | 0.74 to 3.84 | 1.61 | 0.69 to 3.75 | ||
*Adjusted for age, dyslipidaemia, stroke, hypertension, coronary artery disease, diabetes, history of antiplatelet consumption, smoking, ejection fraction <50% and creatinine.
†p for linear trend.
MPV, mean platelet volume.