Table 4

Correlation between autoantibody levels and cardiovascular risk factors and cells of adaptive immune response and cytokines

Antibody	ApoB100		HSP60		HSP60 peptide	ApoB100 peptide
Variables	IgG	IgM	IgG	IgM	IgG	IgG
Adaptive immune cells and cytokines
Th17
ACS	−0.17**	−0.06	−0.20**	−0.05	−0.029	−0.082
SA	−0.016	0.001	−0.023	0.043	−0.057	−0.125
CAD	−0.121**	−0.043	−0.161**	−0.032	−0.042	−0.064
Tregs
ACS	0.04	−0.06	0.01	−0.08	−0.143	−0.155
SA	0.064	0.009	0.034	−0.025	−0.248*	−0.0323**
CAD	0.038	−0.024	−0.010	−0.058	−0.175*	−0.187*
IL17
ACS	−0.1	−0.30**	−0.04	−0.27**	−0.092	−0.427**
SA	0.044	0.111	0.056	0.094	0.034	0.002
CAD	0.009	−0.015	0.022	−0.022	−0.236*	−0.135
IL6
ACS	−0.2	−0.21*	−0.12	−0.25*	−0.242*	−0.147
SA	−0.068	−0.265**	−0.132	−0.246*	−0.189	−0.163
CAD	−0.090	−0.197*	−0.104	−0.221**	−0.138	−0.363**
Risk factors
Smoking
ACS	−0.14**	−0.11*	−0.13**	−0.09*	−0.088	−0.232**
SA	−0.055	−0.107	−0.039	−0.088	−0.097	−0.060
CAD	−0.085*	−0.105*	−0.082	−0.087*	−0.093	−0.192*
Hypertension
ACS	−0.07	−0.11*	−0.05	−0.12*	−0.099	−0.068
SA	−0.099	−0.139*	−0.078	−0.196**	0.003	−0.043
CAD	−0.068	−0.099*	−0.062	−0.133**	−0.043	−0.007
Diabetes
ACS	−0.099*	−0.08	−0.07	−0.06	−0.077	0.069
SA	−0.186**	−0.104	−0.190**	−0.157**	−0.083	−0.040
CAD	−0.142**	−0.072	−0.140**	−0.091*	−0.054	0.047
FBS
ACS	−0.1	−0.05	−0.07	−0.04	−0.112	−0.133
SA	−0.110	−0.047	−0.106	−0.086	−0.088	−0.084
CAD	−0.091	−0.035	−0.091	−0.041	−0.113	−0.138

Pearson bivariate correlation was used for correlation of IgG and IgM antibodies with current smoking (CS), hypertension (HPT), diabetes (DBT), fasting blood sugar (FBS), cells of adaptive immune response Th17 and atherogenic antigens.
P value <0.05 was considered significant. *P<0.05; **P<0.01.
ACS, acute coronary syndrome; ApoB, apolipoprotein B; CAD, coronary artery disease; FBS, fasting blood sugar; HSP, heat shock protein; IL, interleukin; LDL, low-density lipoprotein; n; SA, stable angina; Th17, T helper 17 cell; Tregs, regulatory T cells.