Risk of major adverse outcomes in 1896 patients followed to 2 years according to receipt of cardiovascular secondary prevention medications at discharge and attendance at cardiac rehabilitation at 6 months
Outcome | Receipt of secondary prevention medications (discharge and 6 months) | Attendance at cardiac rehabilitation (6 months) | ||||||||||
≥75%, n (%) | <75%, n (%) | P values | OR (95% CI)* | OR (95% CI)† | OR (95% CI)‡ | Yes, n (%) | No, n (%) | P values | OR (95% CI)* | OR (95% CI)† | OR (95% CI)‡ | |
Death | 62 (4.5) | 48 (9.3) | <0.001 | 0.46 (0.31 to 0.69) | 0.56 (0.39 to 0.82) | 0.64 (0.41 to 0.99) | 15 (2.0) | 95 (8.4) | <0.001 | 0.23 (0.13 to 0.39) | 0.27 (0.16 to 0.45) | 0.34 (0.19 to 0.59) |
MACE | 78 (5.7) | 37 (7.2) | 0.22 | 0.78 (0.60 to 1.02) | 0.89 (0.72 to 1.11) | 1.03 (0.81 to 1.31) | 29 (3.8) | 86 (7.6) | <0.001 | 0.49 (0.33 to 0.73) | 0.55 (0.38 to 0.79) | 0.67 (0.45 to 1.01) |
Death or MACE | 115 (8.3) | 72 (13.9) | <0.001 | 0.56 (0.43 to 0.74) | 0.65 (0.51 to 0.84) | 0.75 (0.56 to 0.99) | 35 (4.6) | 152 (13.4) | <0.001 | 0.31 (0.22 to 0.44) | 0.36 (0.26 to 0.48) | 0.44 (0.31 to 0.62) |
Rehospitalisation | 332 (24.1) | 106 (20.5) | 0.10 | 1.25 (0.95 to 1.64) | 1.31 (1.01 to 1.72) | 1.47 (1.17 to 1.86) | 157 (20.7) | 281 (24.7) | 0.04 | 0.81 (0.65 to 1.01) | 0.84 (0.69 to 1.03) | 0.97 (0.8 to 1.17) |
*Unadjusted.
†Adjusted for sex and age.
‡Adjusted for age, sex, revascularisation, previous cardiovascular disease and GRACE risk score.
CI, confidence interval; GRACE, Global Registry of Acute Coronary Events; MACE, major adverse cardiovascular event; OR, odds ratio.