Table 1

Comparison of major variables and univariate analysis among patients undergoing elective coronary angiography (CAG) according to type of indication for the procedure (with or without heart failure with reduced ejection fraction (HFrEF)). n=2235

ParametersOverall
n= 2235
HFrEF not a CAG
indication
n=1975 (88.4%)
HFrEF as CAG
indication
n=260 (11.6%)
OR (95% CI)P value
Age (years)57.60±9.957.4±9.657.1±10.50.83 (0.6 to 1.13)0.08
Females478 (21.4)415 (21.0)63 (24.2)0.8 (0.6 to 1.1)0.26
Prior heart failure81 (3.6)28 (1.4)53 (20.4)17.8 (11.0 to 28.8)<0.001
Smoker397 (17.8)357 (18.1)40 (15.4)0.82 (0.58 to 1.2)0.30
Dyslipidaemia799 (35.7)741 (37.5)58 (22.3)0.48 (0.35 to 0.65)<0.001
Hypertension1578 (70.6)1411 (71.4)167 (64.2)0.72 (0.55 to 0.94)0.01
Family history of premature CAD504 (22.6)461 (23.3)43 (16.5)0.65 (0.46 to 0.92)0.007
Diabetes mellitus1155 (51.7)1010 (51.1)145 (55.8)1.20 (0.93 to 1.56)0.16
History of chest pain1539 (68.9)1471 (74.5)68 (26.2)0.12 (0.09 to 0.16)<0.001
Non-invasive stress test1025 (46.4)972 (49.2)53 (20.4)0.26 (0.19 to 0.36)<0.001
Positive NIV result (out of total performed)937 (91.3)893 (91.6)44 (88.2)0.68 (0.33 to 1.42)0.12
Any obstructive CAD*1735 (77.6)1613 (81.6)122 (46.9)†0.19 (0.15 to 0.26)<0.001
  • *Any epicardial vessel >2 mm with more than 70% or left main >50% stenosis.

  • †According to Felker et al’ definition, obstructive CAD was 45.8%.

  • CAD, coronary artery disease; NIV, non-invasive.