Table 4

Association of CP ≥1800 mm*ms with time to events in patients with heart failure with preserved ejection fraction

HR95% CIP value
Time to all-cause death
 Unadjusted2.671.23 to 5.790.013
 Adjusted2.911.14 to 7.420.026
Time to first heart failure hospitalisation
 Unadjusted1.951.16 to 3.270.012
 Adjusted1.971.04 to 3.680.037
Time to composite*
 Unadjusted2.081.33 to 3.250.001
 Adjusted2.061.21 to 3.510.008
  • Multivariate adjustment of CP ≥1800 mm*ms with clinical, echocardiographic and NT-proBNP for various outcomes.

  • Adjusted models: adjusted for age per 10 years, sex, ethnicity, systolic blood pressure per 10 mm Hg, heart rate per 10 beats per minute, logNT-proBNP, E/e′ and left ventricular mass index.

  • *Composite of all-cause death and heart failure hospitalisation.

  • CP, Cornell product; E/e', Average mitral annular E velocity to e' ratio; NT-proBNP, N-terminal pro B-type natriuretic peptide.