Incidence of clinical events during follow-up (per 100 person-years)
| Total (n=240) | Frail (n=120) | Non-frail (n=120) | P value* | |
| Stroke/SE/Major bleeding /all-cause mortality | 14.0 | 30.2 | 4.8 | <0.001 |
| Stroke/SE | 2.6 | 6.2 | 0.6 | 0.024 |
| Major bleeding | 4.2 | 8.3 | 1.8 | 0.038 |
| All-cause death | 7.6 | 16.6 | 2.4 | <0.001 |
| Cardiac death | 1.5 | 2.1 | 1.2 | 0.583 |
| Non-cardiac death | 6.0 | 14.6 | 1.2 | <0.001 |
Frail, CFS 5–9; non-frail, CFS 1–4.
*P value for comparison between frail and non-frail from log-rank test.
CFS, Clinical Frailty Scale; SE, systemic embolism.