Arrhythmias and conduction disturbancesUsefulness of Ventricular Premature Complexes to Predict Coronary Heart Disease Events and Mortality (from the Atherosclerosis Risk In Communities Cohort)
Section snippets
Methods and Results
The study population consisted of participants in the Atherosclerosis Risk In Communities (ARIC) study, a population-based prospective cohort of approximately 4,000 adults residing in each of 4 United States communities (Forsyth County, North Carolina; Jackson, Mississippi; selected suburbs of Minneapolis, Minnesota; and Washington County, Maryland). The ARIC study was designed to investigate the etiology of atherosclerosis and cardiovascular disease and their relations to race, gender, risk
Discussion
Patients with VPCs are substantially more likely to develop subsequent CHD events and mortality compared with patients without VPCs. These risks are statistically independent of CHD risk factors. VPC-associated risk is not confined to patients with established CHD, but is also found among apparently healthy patients without history or clinical manifestations of CHD.
Our finding that VPCs are associated with CHD and death illuminates a fundamental clinical concern. Randomized trials have shown
Acknowledgment
The investigators thank the staff and participants of the ARIC study for important contributions.
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2019, Biomedical Signal Processing and ControlCitation Excerpt :A PVC beat is a pulse that appears earlier than the subsequent coming sinus pulse. PVC beats can appear in normal healthy persons, but in diseased hearts, the frequency of appearance in an ECG is increased and can be an indicator of a life threatening condition [14,15]. The main causes of PVCs and their complex samples in the heart are still poorly understood [16].
2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
2018, Journal of the American College of Cardiology2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society
2018, Journal of the American College of Cardiology
The Atherosclerosis Risk In Communities Study is carried out as a collaborative study supported by Contracts N01-HC-55015, N01-HC-55016, N01-HC-55018, N01-HC-55019, N01-HC-55020, N01-HC-55021, and N01-HC-55022 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland. This research was supported by Contracts N01-HC-55018, N01-HC-55019, N01-HC-55020, N01-HC-55021, and N01-HC-55022 from the National Heart, Lung, and Blood Institute. Further support for Dr. Massing included a National Research Award Grant 5-T32-HL007055 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland.