Original articleCardiovascularResults and Predictors of Early and Late Outcome of Coronary Artery Bypass Grafting in Patients With Severely Depressed Left Ventricular Function
Section snippets
Study Population
We analyzed a series of 2,725 patients undergoing isolated CABG procedures at the Mount Sinai Medical Center between January 1998 and December 2005. Data were prospectively collected and analyzed retrospectively.
The study group was determined by the preoperative EF. Patients with an EF less than or equal to 0.30 formed the study group, whereas patients with an EF greater than 0.30 served as the control group. Patients undergoing reoperations or emergent procedures were included in this
Demographic Data and Preoperative Risk Factors
The median age in the overall patient population was 66 years (interquartile range, 58–73 years), and 69% (n = 1,882) of patients were male. Severely depressed LV function (EF ≤ 0.30) was present in 495 (18%) patients.
There were significant differences in preoperative comorbidity between patients with EF of 0.30 or less and those with EF greater than 0.30 (Table 1). Patients with EF of 0.30 or less were more likely to present with congestive heart failure (p < 0.001), a history of myocardial
Comment
In this observational study, we report our experience in a large and contemporary series of patients with severely depressed LV function undergoing CABG. The main findings of this study include very low operative mortality, which declined across the study period despite a statistically significant increase in the percentage of patients with high predicted mortality risk by logistic EuroSCORE. We show that severely depressed LV function does not appear to be an independent predictor of early
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