Journal of the American Society of Echocardiography
Factors associated with mitral annular systolic and diastolic velocities in healthy adults
Section snippets
Participants
The study design was approved by the institutional human research and ethics committee and written consent was obtained from the participants. The study group comprised 60 healthy participants between the ages of 20 and 52 years (mean age, 33 ± 8 years), half of whom were men. Participants were not eligible if they had a history of cardiac disease or hypertension. Height and weight were measured immediately before the echocardiographic study. Body surface area (BSA) was calculated using the
Participant group characteristics
In our cohort, participant height ranged from 156 to 195 cm, weight ranged from 49 to 101 kg, systolic BP ranged from 85 to 130 mm Hg, diastolic BP ranged from 50 to 90 mm Hg, and HR ranged from 42/min to 92/min. Of the derived measurements, BSA ranged from 1.47 to 2.34 m2, BMI ranged from 18.4 to 28.7 kg/m2, and LV mass ranged from 80 to 292 g.
The univariate correlations of LV end-diastolic diameter (LVEDD), LV mass, LV mass/height, LV mass/height2.7, and LV mass/BSA with age, sex, BP, and
Discussion
In this study, performed in a healthy cohort of participants between 20 and 52 years without cardiac disease, obesity, or hypertension, we examined the relationship among S′, E′, and A′ at the septal and lateral annulus and also the association of S′, E′, and A′ with body size, HR, BP, and LV mass. There were 4 important new findings of this study. First, not only did we confirm previous reports that the S′, E′, and A′ at the septal annulus are significantly lower than the lateral annulus, but
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