Original ArticleRisk Factor Profiles of Stroke, Myocardial Infarction, and Atrial Fibrillation: A Japanese Multicenter Cooperative Registry
Section snippets
Patients Recruited
Recruitment was started in January 2005 and terminated in December 2006. The study protocol was reviewed by an institutional review board (IRB) at each site. A central IRB reviewed the study for those sites that did not have their own internal IRB. All patients gave informed consent after receiving a full explanation of the study from the investigators. Patients aged 20 to 90 years with history of stroke, MI, or NVAF were eligible to be enrolled in J-TRACE. Inclusion criteria for history of
Results
A total of 8087 patients were recruited into the J-TRACE from 201 sites. They included 3554 patients with history of stroke, 2291 patients with history of MI, and 2242 patients with history of NVAF. Table 1 shows the baseline characteristics of the recruited patients by disease category. Mean age was youngest for patients with MI and oldest for patients with NVAF. Male percentage was more than approximately 10% higher for MI than for stroke and NVAF. Prevalence of risk factors exhibited
Discussion
J-TRACE, a large nationwide multicenter cooperative registry, is unique in simultaneous recruitment of not only patients with stroke and MI but also those with NVAF, which are 3 major thromboembolic diseases that cause death or disability in the Japanese population, in order to prospectively investigate vascular event rates during a 3-year follow-up period. In this study, we examined baseline data to clarify risk factor profiles and present status of risk factor management and antithrombotic
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Supported by the Japan Heart Foundation.