Cardiopulmonary support and physiologyTransplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis
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Abbreviations and Acronyms
dp/dt
rate of pressure rise
EPO
erythropoietin
EPOR
cognate receptor of erythropoietin
GFP
green fluorescent protein
HIF-1α
hypoxia-inducible factor-1α
H-MSC
hypoxic mesenchymal stem cell
HP
hypoxic preconditioning
LVEDP
left ventricular end-diastolic pressure
LVSP
left ventricular systolic pressure
MI
myocardial infarction
MSC
mesenchymal stem cell
N-MSC
normoxic mesenchymal stem cell
PBS
phosphate-buffered saline solution
TUNEL
terminal deoxynucleotidyl transferase biotin-dUPT nick end labeling
VEGF
vascular endothelial growth factor
CTSNet classification
30
31
34
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This work was supported by National Institutes of Health grants NS 37372, NS 045155, and NS 045810 and American Heart Association and Bugher Foundation (AHA-Bugher) Awards 0170064N and 0170063N. The work was also supported by National Institutes of Health grant C06 RR015455 from the Extramural Research Facilities Program of the National Center for Research Resources.
Copyright © 2008 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.