Abstract
In a matched case-control study using the General Practice Research Database, current statin use was not associated with a significantly altered risk of any of 13 studied cancers. Untreated hyperlipidaemia was associated with slightly increased risks of colon cancer (relative risk 1.8; 95% confidence interval 1.2-2.8), prostate cancer (1.5; 1.1-2.0), and bladder cancer (1.9; 1.2-3.1).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Aged, 80 and over
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Case-Control Studies
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Colonic Neoplasms / epidemiology
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Colonic Neoplasms / etiology
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Databases, Factual / statistics & numerical data
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Female
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Humans
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / pharmacology
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
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Hyperlipidemias / complications
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Incidence
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Male
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Middle Aged
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Neoplasms / epidemiology*
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Neoplasms / etiology*
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Prostatic Neoplasms / epidemiology
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Prostatic Neoplasms / etiology
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Risk Factors
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Urinary Bladder Neoplasms / epidemiology
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Urinary Bladder Neoplasms / etiology
Substances
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Hydroxymethylglutaryl-CoA Reductase Inhibitors