User profiles for "author:Harry Klimis"
Harry KlimisClinical Lecturer, University of Sydney Verified email at sydney.edu.au Cited by 662 |
Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with …
Background Treatment inertia is a recognised barrier to blood pressure control, and simpler,
more effective treatment strategies are needed. We hypothesised that a hypertension …
more effective treatment strategies are needed. We hypothesised that a hypertension …
Breaking barriers: mobile health interventions for cardiovascular disease
H Klimis, J Thakkar, CK Chow - Canadian Journal of Cardiology, 2018 - Elsevier
Cardiovascular disease (CVD) is a leading global cause of death and morbidity and
prevention needs to be strengthened to tackle this. Mobile health (mHealth) might present a …
prevention needs to be strengthened to tackle this. Mobile health (mHealth) might present a …
Diagnostic accuracy of handheld electrocardiogram devices in detecting atrial fibrillation in adults in community versus hospital settings: a systematic review and meta …
With increasing use of handheld ECG devices for atrial fibrillation (AF) screening, it is
important to understand their accuracy in community and hospital settings and how it differs …
important to understand their accuracy in community and hospital settings and how it differs …
Machine-learning versus traditional approaches for atherosclerotic cardiovascular risk prognostication in primary prevention cohorts: a systematic review and meta …
Background Cardiovascular disease (CVD) risk prediction is important for guiding the
intensity of therapy in CVD prevention. Whilst current risk prediction algorithms use …
intensity of therapy in CVD prevention. Whilst current risk prediction algorithms use …
Are α9α10 nicotinic acetylcholine receptors a pain target for α-conotoxins?
The synthetic α-conotoxin Vc1. 1 is a small disulfide bonded peptide currently in
development as a treatment for neuropathic pain. Unlike Vc1. 1, the native post …
development as a treatment for neuropathic pain. Unlike Vc1. 1, the native post …
Text messages to improve medication adherence and secondary prevention after acute coronary syndrome: the TEXTMEDS randomized clinical trial
CK Chow, H Klimis, A Thiagalingam, J Redfern… - Circulation, 2022 - Am Heart Assoc
Background: TEXTMEDS (Text Messages to Improve Medication Adherence and Secondary
Prevention After Acute Coronary Syndrome) examined the effects of text message–delivered …
Prevention After Acute Coronary Syndrome) examined the effects of text message–delivered …
A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain
α-Conotoxins that are thought to act as antagonists of nicotinic acetylcholine receptors
(nAChRs) containing α3-subunits are efficacious in several preclinical models of chronic …
(nAChRs) containing α3-subunits are efficacious in several preclinical models of chronic …
Intrathecal α-conotoxins Vc1. 1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain
The large diversity of peptides from venomous creatures with high affinity for molecules
involved in the development and maintenance of neuropathic pain has led to a surge in …
involved in the development and maintenance of neuropathic pain has led to a surge in …
Text messages for primary prevention of cardiovascular disease: the TextMe2 randomized clinical trial
H Klimis, A Thiagalingam, D McIntyre, S Marschner… - American Heart …, 2021 - Elsevier
Background Primary prevention guidelines emphasize the importance of lifestyle
modification, but many at high-risk have suboptimal cardiovascular risk factor (CVRF) …
modification, but many at high-risk have suboptimal cardiovascular risk factor (CVRF) …
The burden of uncontrolled cardiovascular risk factors in men with prostate cancer: a RADICAL-PC analysis
Background Cardiovascular disease (CVD) incidence is higher in men with prostate cancer
(PC) than without. Objectives We describe the rate and correlates of poor cardiovascular risk …
(PC) than without. Objectives We describe the rate and correlates of poor cardiovascular risk …