The global burden of disease caused by group A streptococcus (GAS) is not known. We
review recent population-based data to estimate the burden of GAS diseases and highlight …

Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are
the leading cause of global mortality and a major contributor to disability. This paper reviews …

Acute rheumatic fever (ARF) and its chronic sequela, rheumatic heart disease (RHD), have
become rare in most affluent populations, but remain unchecked in developing countries …

Background As mortality rates decline, life expectancy increases, and populations age, non-
fatal outcomes of diseases and injuries are becoming a larger component of the global …

Background Quantification of the disease burden caused by different risks informs
prevention by providing an account of health loss different to that provided by a disease-by …

Background Measuring disease and injury burden in populations requires a composite
metric that captures both premature mortality and the prevalence and severity of ill-health …

Background Non-fatal health outcomes from diseases and injuries are a crucial
consideration in the promotion and monitoring of individual and population health. The …

Background Reliable and timely information on the leading causes of death in populations,
and how these are changing, is a crucial input into health policy debates. In the Global …

Summary Background The Global Burden of Disease Study 2013 (GBD 2013) aims to bring
together all available epidemiological data using a coherent measurement framework …

Background: The burden of cardiovascular diseases (CVDs) remains unclear in many
regions of the world. Objectives: The GBD (Global Burden of Disease) 2015 study integrated …