[HTML][HTML] Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway

QF Fu, Y Liu, Y Fan, SN Hua, HY Qu, SW Dong… - Journal of hematology & …, 2015 - Springer
Background During tumor formation and expansion, increasing glucose metabolism is
necessary for unrestricted growth of tumor cells. Expression of key glycolytic enzyme alpha …

[HTML][HTML] Silencing MYH9 blocks HBx-induced GSK3β ubiquitination and degradation to inhibit tumor stemness in hepatocellular carcinoma

X Lin, A Li, YH Li, RC Luo, YJ Zou, YY Liu… - Signal transduction and …, 2020 - nature.com
MYH9 has dual functions in tumors. However, its role in inducing tumor stemness in
hepatocellular carcinoma (HCC) is not yet determined. Here, we found that MYH9 is an …

A novel NKX2. 5 loss-of-function mutation associated with congenital bicuspid aortic valve

XK Qu, XB Qiu, F Yuan, J Wang, CM Zhao… - The American journal of …, 2014 - Elsevier
Bicuspid aortic valve (BAV) is the most common form of congenital cardiovascular defect in
humans and is associated with substantial morbidity and mortality. Emerging evidence …

GATA 4 Loss‐of‐Function Mutations Underlie Familial Tetralogy of Fallot

YQ Yang, L Gharibeh, RG Li, YF Xin, J Wang… - Human …, 2013 - Wiley Online Library
Tetralogy of Fallot (TOF) represents the most common form of cyanotic congenital heart
disease and accounts for significant morbidity and mortality in humans. Emerging evidence …

[HTML][HTML] Mutations of the SCN4B-encoded sodium channel β4 subunit in familial atrial fibrillation

RG Li, Q Wang, YJ Xu, M Zhang… - International …, 2013 - spandidos-publications.com
Atrial fibrillation (AF) represents the most common form of sustained cardiac arrhythmia and
accounts for substantial morbidity and mortality. Mutations in the cardiac sodium channel α …

Reexploring the possible roles of some genes associated with nasopharyngeal carcinoma using microarray-based detection

WY Fang, TF Liu, WB Xie, XY Yang… - Acta biochimica et …, 2005 - academic.oup.com
Abstract Opinion 2/13, by which the CJEU declared incompatible with the EU treaties the
long-negotiated draft agreement on EU accession to the ECHR, came as a shock to many …

Novel Germline GJA5/Connexin40 Mutations Associated with Lone Atrial Fibrillation Impair Gap Junctional Intercellular Communication

Y Sun, YQ Yang, XQ Gong, XH Wang, RG Li… - Human …, 2013 - Wiley Online Library
Atrial fibrillation (AF) is the most common form of sustained cardiac arrhythmia worldwide.
Here, we investigate the molecular and cellular mechanisms of lone AF‐linked germline …

GATA4 loss-of-function mutations in familial atrial fibrillation

YQ Yang, MY Wang, XL Zhang, HW Tan, HF Shi… - Clinica chimica acta, 2011 - Elsevier
BACKGROUND: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and
a major source of the substantially increased morbidity and mortality. Growing studies …

The small molecule chemical compound cinobufotalin attenuates resistance to DDP by inducing ENKUR expression to suppress MYH9-mediated c-Myc …

J Liu, H Yang, S Deng, Z Hu, W Chen, W Yan… - Acta pharmacologica …, 2022 - nature.com
The small molecule chemical compound cinobufotalin (CB) is reported to be a potential
antitumour drug that increases cisplatin (DDP) sensitivity in nasopharyngeal carcinoma. In …

Novel connexin40 missense mutations in patients with familial atrial fibrillation

YQ Yang, X Liu, XL Zhang, XH Wang, HW Tan… - Europace, 2010 - academic.oup.com
Aims This research was aimed at screening connexin40, a cardiac gap junction protein
alpha 5, for genetic defects in patients with familial atrial fibrillation (AF). Methods The …