Bicuspid aortic valve (BAV) is the most common form of congenital cardiovascular defect in
humans and is associated with substantial morbidity and mortality. Emerging evidence …

Congenital heart disease (CHD) is the most common developmental abnormality, and is the
leading noninfectious cause of mortality in neonates. Increasing evidence demonstrates that …

The cardiac T-box transcription factor TBX5 is crucial for proper cardiovascular
development, and mutations in TBX5 have been associated with various congenital heart …

Previous genome-wide association studies have demonstrated that single nucleotide
polymorphisms in T‑box (TBX) 5 are associated with increased susceptibility to atrial …

Congenital heart disease (CHD) is the most prevalent type of birth defect in humans and is
the leading non-infectious cause of infant death worldwide. There is a growing body of …

Introduction N-acetylcysteine (NAC) and sodium bicarbonate (SOB) therapies may prevent
contrast-induced nephropathy (CIN). However, the efficacy of using combination over …

Background: The zinc finger transcription factor CASZ1 plays a key role in cardiac
development and postnatal adaptation, and in mice, deletion of the CASZ1 gene leads to …

Congenital atrial septal defect (ASD) and progressive atriventricular block (AVB) are the two
most common phenotypes linked to NK2 homeobox 5 (NKX2. 5) mutations in animals and …

Background Mineralocorticoid receptor (MR) antagonists have been widely used to treat
heart failure (HF). Studies have shown that MR in T cells plays important roles in …

The study aimed at testing the hypothesis that tongxinluo capsule might exert its
cardioprotective effect by preventing ventricular remodeling and improving coronary …